{"id":10143,"date":"2025-09-23T22:27:07","date_gmt":"2025-09-23T22:27:07","guid":{"rendered":"https:\/\/atlasemhematologia.com.br\/?p=10143"},"modified":"2026-03-24T20:01:21","modified_gmt":"2026-03-24T20:01:21","slug":"anemia-falciforme","status":"publish","type":"post","link":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/","title":{"rendered":"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA"},"content":{"rendered":"\n

A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de hemoglobina S (HbS). Essa hemoglobina S se origina de uma substitui\u00e7\u00e3o de bases nitrogenadas, que altera o \u00e1cido glut\u00e2mico por valina na posi\u00e7\u00e3o 6 do gene da globina beta, localizado no cromossomo 11. Em condi\u00e7\u00f5es de baixo oxig\u00eanio, a valina mutante exp\u00f5e-se e interage com amino\u00e1cidos de outras globinas beta, iniciando o fen\u00f4meno da polimeriza\u00e7\u00e3o, que modifica a forma dos eritr\u00f3citos, tornando-os alongados e, por vezes, curvos, com um formato semelhante \u00e0 foice:<\/p>\n\n\n\n

\"anemia
Drepan\u00f3citos em doen\u00e7a falciforme. Fonte: Cellwiki<\/em><\/figcaption><\/figure>\n\n\n\n

Na anemia falciforme, a mudan\u00e7a na forma das hem\u00e1cias afeta a fun\u00e7\u00e3o da bomba Na+\/K+, levando \u00e0 perda de pot\u00e1ssio e \u00e1gua, tornando as hem\u00e1cias mais densas e. H\u00e1 tamb\u00e9m um aumento do c\u00e1lcio intracelular, pois a bomba de Ca2+\/ATPase deixa de funcionar, resultando em maior concentra\u00e7\u00e3o de hemoglobina corpuscular m\u00e9dia (CHCM) e redu\u00e7\u00e3o da permeabilidade celular. Essas altera\u00e7\u00f5es cont\u00ednuas na forma das hem\u00e1cias causam danos cr\u00f4nicos \u00e0 membrana celular, tornando-as irreversivelmente falciformes. <\/p>\n\n\n\n

A vaso-oclus\u00e3o come\u00e7a com a ader\u00eancia das c\u00e9lulas falciformes ao endot\u00e9lio vascular, seguida pelo ac\u00famulo de c\u00e9lulas menos deformadas. A oclus\u00e3o microvascular est\u00e1 relacionada \u00e0 concentra\u00e7\u00e3o de pol\u00edmeros de HbS formados. A ader\u00eancia de hem\u00e1cias falciformes ao endot\u00e9lio vascular causa hip\u00f3xia tecidual, aumentando a presen\u00e7a de HbS desoxi e resultando em mais danos aos tecidos.<\/p>\n\n\n\n

Os fosfolip\u00eddios, presentes na superf\u00edcie interna da membrana das hem\u00e1cias, sofrem assimetria na doen\u00e7a falciforme, expondo a fosfatidilserina. Isso ativa prote\u00ednas de coagula\u00e7\u00e3o e plaquetas, aumenta a express\u00e3o de mol\u00e9culas de ades\u00e3o no endot\u00e9lio vascular e contribui para a anemia, pois as c\u00e9lulas falciformes s\u00e3o removidas pelo sistema fagocit\u00e1rio, reduzindo seu tempo de vida na corrente sangu\u00ednea.<\/p>\n\n\n\n

A atividade fibrinol\u00edtica pode causar crises dolorosas em pacientes com anemia falciforme. As plaquetas circulantes permanecem cronicamente ativadas, mantendo um estado hipercoagul\u00e1vel. No entanto, durante crises dolorosas agudas, observa-se uma redu\u00e7\u00e3o na sobrevida das plaquetas, provavelmente devido \u00e0 deposi\u00e7\u00e3o plaquet\u00e1ria nas paredes do endot\u00e9lio vascular.<\/p>\n\n\n\n

Portanto, a compreens\u00e3o das altera\u00e7\u00f5es na Anemia Falciforme \u00e9 crucial para a gest\u00e3o eficaz da doen\u00e7a e a redu\u00e7\u00e3o das complica\u00e7\u00f5es associadas. Abordagens terap\u00eauticas que visam n\u00e3o apenas a corre\u00e7\u00e3o dos sintomas hematol\u00f3gicos, mas tamb\u00e9m a modula\u00e7\u00e3o dos mecanismos hemost\u00e1ticos, s\u00e3o fundamentais para melhorar a qualidade de vida dos portadores.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Refer\u00eancias<\/strong><\/h3>\n\n\n\n

ZAGO, Marco Antonio; FALC\u00c3O, Roberto Passetto; PASQUINI, Ricardo. Hematologia fundamentos e pr\u00e1tica. In: Hematologia fundamentos e pr\u00e1tica. 2005. p. 1101-1101.<\/p>\n\n\n\n

Stypulkowski JB, Manfredini V. Altera\u00e7\u00f5es hemost\u00e1sticas em pacientes com doen\u00e7a falciforme. Associa\u00e7\u00e3o Brasileira de Hematologia e Hemoterapia, 2010. <\/p>\n\n\n\n

NAOUM, Fl\u00e1vio Augusto. Doen\u00e7as que alteram os exames hematol\u00f3gicos. 2. ed. Rio de Janeiro: Atheneu, 2017.<\/p>\n","protected":false},"excerpt":{"rendered":"

A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de hemoglobina S (HbS). Essa hemoglobina S se origina de uma substitui\u00e7\u00e3o de bases nitrogenadas, que altera o \u00e1cido glut\u00e2mico por valina na posi\u00e7\u00e3o 6 do gene da globina beta, localizado no cromossomo 11. Em condi\u00e7\u00f5es […]<\/p>\n","protected":false},"author":3,"featured_media":17083,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pagelayer_contact_templates":[],"_pagelayer_content":"","footnotes":""},"categories":[14,12],"tags":[],"class_list":["post-10143","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anemias","category-hemostasia"],"yoast_head":"\nANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA - Blog - Atlas em Hematologia<\/title>\n<meta name=\"description\" content=\"A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA - Blog - Atlas em Hematologia\" \/>\n<meta property=\"og:description\" content=\"A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de\" \/>\n<meta property=\"og:url\" content=\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\" \/>\n<meta property=\"og:site_name\" content=\"Blog - Atlas em Hematologia\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-23T22:27:07+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-24T20:01:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Thiago Alcantara\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Thiago Alcantara\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\"},\"author\":{\"name\":\"Thiago Alcantara\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/person\/81c81f9c3605c9d9574cea18d2809865\"},\"headline\":\"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA\",\"datePublished\":\"2025-09-23T22:27:07+00:00\",\"dateModified\":\"2026-03-24T20:01:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\"},\"wordCount\":522,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png\",\"articleSection\":[\"ANEMIAS\",\"HEMOSTASIA\"],\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\",\"url\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\",\"name\":\"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA - Blog - Atlas em Hematologia\",\"isPartOf\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png\",\"datePublished\":\"2025-09-23T22:27:07+00:00\",\"dateModified\":\"2026-03-24T20:01:21+00:00\",\"description\":\"A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de\",\"breadcrumb\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage\",\"url\":\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png\",\"contentUrl\":\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png\",\"width\":1080,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\/\/atlasemhematologia.com.br\/blog\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#website\",\"url\":\"https:\/\/atlasemhematologia.com.br\/blog\/\",\"name\":\"Blog - Atlas em Hematologia\",\"description\":\"Blog - Atlas em Hematologia\",\"publisher\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/atlasemhematologia.com.br\/blog\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#organization\",\"name\":\"Blog - Atlas em Hematologia\",\"url\":\"https:\/\/atlasemhematologia.com.br\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/Logo-TA-Horizontal-1-scaled.png\",\"contentUrl\":\"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/Logo-TA-Horizontal-1-scaled.png\",\"width\":2560,\"height\":886,\"caption\":\"Blog - Atlas em Hematologia\"},\"image\":{\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/person\/81c81f9c3605c9d9574cea18d2809865\",\"name\":\"Thiago Alcantara\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/secure.gravatar.com\/avatar\/efb1e9db30768e7f0006b192876bddba4cbee63a76ac7d8f40e353fd05de0f16?s=96&d=mm&r=g\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/efb1e9db30768e7f0006b192876bddba4cbee63a76ac7d8f40e353fd05de0f16?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/efb1e9db30768e7f0006b192876bddba4cbee63a76ac7d8f40e353fd05de0f16?s=96&d=mm&r=g\",\"caption\":\"Thiago Alcantara\"},\"url\":\"https:\/\/atlasemhematologia.com.br\/blog\/author\/thiago\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA - Blog - Atlas em Hematologia","description":"A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/","og_locale":"pt_BR","og_type":"article","og_title":"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA - Blog - Atlas em Hematologia","og_description":"A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de","og_url":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/","og_site_name":"Blog - Atlas em Hematologia","article_published_time":"2025-09-23T22:27:07+00:00","article_modified_time":"2026-03-24T20:01:21+00:00","og_image":[{"width":1080,"height":1080,"url":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png","type":"image\/png"}],"author":"Thiago Alcantara","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"Thiago Alcantara","Est. tempo de leitura":"3 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#article","isPartOf":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/"},"author":{"name":"Thiago Alcantara","@id":"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/person\/81c81f9c3605c9d9574cea18d2809865"},"headline":"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA","datePublished":"2025-09-23T22:27:07+00:00","dateModified":"2026-03-24T20:01:21+00:00","mainEntityOfPage":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/"},"wordCount":522,"commentCount":0,"publisher":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/#organization"},"image":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage"},"thumbnailUrl":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png","articleSection":["ANEMIAS","HEMOSTASIA"],"inLanguage":"pt-BR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/","url":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/","name":"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA - Blog - Atlas em Hematologia","isPartOf":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage"},"image":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage"},"thumbnailUrl":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png","datePublished":"2025-09-23T22:27:07+00:00","dateModified":"2026-03-24T20:01:21+00:00","description":"A anemia falciforme \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica provocada por uma muta\u00e7\u00e3o no gene da hemoglobina beta, resultando na forma\u00e7\u00e3o de","breadcrumb":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/"]}]},{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#primaryimage","url":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png","contentUrl":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/ANEMIA-FALCIFORME-E-ALTERACOES-NA-HEMOSTASIA.png","width":1080,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/atlasemhematologia.com.br\/blog\/anemia-falciforme\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/atlasemhematologia.com.br\/blog\/"},{"@type":"ListItem","position":2,"name":"ANEMIA FALCIFORME E ALTERA\u00c7\u00d5ES NA HEMOSTASIA"}]},{"@type":"WebSite","@id":"https:\/\/atlasemhematologia.com.br\/blog\/#website","url":"https:\/\/atlasemhematologia.com.br\/blog\/","name":"Blog - Atlas em Hematologia","description":"Blog - Atlas em Hematologia","publisher":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/atlasemhematologia.com.br\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/atlasemhematologia.com.br\/blog\/#organization","name":"Blog - Atlas em Hematologia","url":"https:\/\/atlasemhematologia.com.br\/blog\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/Logo-TA-Horizontal-1-scaled.png","contentUrl":"https:\/\/atlasemhematologia.com.br\/blog\/wp-content\/uploads\/2025\/09\/Logo-TA-Horizontal-1-scaled.png","width":2560,"height":886,"caption":"Blog - Atlas em Hematologia"},"image":{"@id":"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/atlasemhematologia.com.br\/blog\/#\/schema\/person\/81c81f9c3605c9d9574cea18d2809865","name":"Thiago Alcantara","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/secure.gravatar.com\/avatar\/efb1e9db30768e7f0006b192876bddba4cbee63a76ac7d8f40e353fd05de0f16?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/efb1e9db30768e7f0006b192876bddba4cbee63a76ac7d8f40e353fd05de0f16?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/efb1e9db30768e7f0006b192876bddba4cbee63a76ac7d8f40e353fd05de0f16?s=96&d=mm&r=g","caption":"Thiago Alcantara"},"url":"https:\/\/atlasemhematologia.com.br\/blog\/author\/thiago\/"}]}},"_links":{"self":[{"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/posts\/10143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/comments?post=10143"}],"version-history":[{"count":2,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/posts\/10143\/revisions"}],"predecessor-version":[{"id":17326,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/posts\/10143\/revisions\/17326"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/media\/17083"}],"wp:attachment":[{"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/media?parent=10143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/categories?post=10143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/atlasemhematologia.com.br\/blog\/wp-json\/wp\/v2\/tags?post=10143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}