{"version":"1.0","provider_name":"Blog - Atlas em Hematologia","provider_url":"https:\/\/atlasemhematologia.com.br\/blog","author_name":"Thiago Alcantara","author_url":"https:\/\/atlasemhematologia.com.br\/blog\/author\/thiago\/","title":"S\u00cdNDROME DE CH\u00c9DIAK-HIGASHI: ALTERA\u00c7\u00d5ES HEMATOL\u00d3GICAS - Blog - Atlas em Hematologia","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"aQN1x2BVpB\"><a href=\"https:\/\/atlasemhematologia.com.br\/blog\/sindrome-de-chediak-higashi\/\">S\u00cdNDROME DE CH\u00c9DIAK-HIGASHI: ALTERA\u00c7\u00d5ES HEMATOL\u00d3GICAS<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/atlasemhematologia.com.br\/blog\/sindrome-de-chediak-higashi\/embed\/#?secret=aQN1x2BVpB\" width=\"600\" height=\"338\" title=\"&#8220;S\u00cdNDROME DE CH\u00c9DIAK-HIGASHI: ALTERA\u00c7\u00d5ES HEMATOL\u00d3GICAS&#8221; &#8212; Blog - Atlas em Hematologia\" data-secret=\"aQN1x2BVpB\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/atlasemhematologia.com.br\/blog\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","thumbnail_url":null,"thumbnail_width":null,"thumbnail_height":null,"description":"A s\u00edndrome de Ch\u00e9diak-Higashi (SCH) \u00e9 uma doen\u00e7a rara, de heran\u00e7a gen\u00e9tica autoss\u00f4mica recessiva, caracterizada por uma falha nas c\u00e9lulas fagoc\u00edticas do sistema imunol\u00f3gico. Ela resulta de uma muta\u00e7\u00e3o no gene LYST, afetando, assim, a capacidade do corpo de destruir bact\u00e9rias fagocitadas. Como resultado, leva a infec\u00e7\u00f5es recorrentes e complica\u00e7\u00f5es hematol\u00f3gicas. Al\u00e9m disso, a s\u00edndrome est\u00e1 associada a albinismo oculocut\u00e2neo e manifesta\u00e7\u00f5es neurol\u00f3gicas. No entanto, \u00e9 no hemograma que as altera\u00e7\u00f5es mais not\u00e1veis se concentram."}